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Edit Cast Series cast summary: Vallery Irons 88 episodes, Molly Culver Tasha Dexter 88 episodes, Shaun Baker Quick Williams 88 episodes, Natalie Raitano Nikki Franco 88 episodes, Leah Lail Kay Simmons 88 episodes, Angelle Brooks Maxine de la Cruz 75 episodes, Dustin Nguyen Edit Storyline Campy syndicated series about Vallery Irons, a girl working at a hotdog stand who accidently saves a celebrity and is mistaken for a bodyguard.
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With respect to the digestive system , VIP seems to induce smooth muscle relaxation lower esophageal sphincter , stomach, gallbladder , stimulate secretion of water into pancreatic juice and bile , and cause inhibition of gastric acid secretion and absorption from the intestinal lumen.
These effects work together to increase motility. It causes coronary vasodilation  as well as having a positive inotropic and chronotropic effect.
Research is being performed to see if it may have a beneficial role in the treatment of heart failure. VIP provokes vaginal lubrication in normal women, doubling the total volume of lubrication produced.
VIP in the pituitary helps to regulate prolactin secretion; it stimulates prolactin release in the domestic turkey. Then it will activate gene expression pathways such as Per1 and Per2 in circadian rhythm.
Sparse GABAergic connections are thought to decrease synchronized firing. Circadian time is likely to affect the synapses rather than the organization of VIP circuits.
The SCN coordinates daily timekeeping in the body and VIP plays a key role in communication between individual brain cells within this region.
At a cellular level, the SCN expresses different electrical activity in circadian time. Higher activity is observed during the day, while during night there is lower activity.
This rhythm is thought to be important feature of SCN to synchronize with each other and control rhythmicity in other regions.
The high concentration of VIP and VIP receptor containing neurons are primarily found in the ventrolateral aspect of the SCN, which is also located above the optic chiasm.
The neurons in this area receive retinal information from the retinohypothalamic tract and then relay the environmental information to the SCN. The VIP also plays a pivotal role in modulating oscillations.
Previous pharmacological research has established that VIP is needed for normal light-induced synchronization of the circadian systems.
Application of VIP also phase shifts the circadian rhythm of vasopressin release and neural activity.
The ability of the population to remain synchronized as well as the ability of single cells to generate oscillations is composed in VIP or VIP receptor deficient mice.
While not highly studied, there is evidence that levels of VIP and its receptor may vary depending on each circadian oscillation. SCN has neural multiple pathways to control and modulate endocrine activity.
VIP and vasopressin are both important for neurons to relay information to different targets and affect neuroendocrine function.
VIP neurons located in the hypothalamus, specifically the dorsal anterior hypothalamus and ventromedial hypothalamus, have an effect on social behaviors in many species of vertebrates.
Studies suggest that VIP cascades can be activated in the brain in response to a social situation that stimulates the areas of the brain that are known to regulate behavior.
This social circuit includes many areas of the hypothalamus along with the amygdala and the ventral tegmental area. The production and release of the neuropeptide VIP is centralized in the hypothalamic and extrahypothalamic regions of the brain and from there it is able to modulate the release of prolactin secretion.
In certain species of birds with a knockout VIP gene there was an observable decrease in overall aggression over nesting territory. While there is existing conflict in whether down-regulation or up-regulation of VIP contributes to OA, VIP has been shown to prevent cartilage damage in animals.
From Wikipedia, the free encyclopedia. Chromosome 6 human .